Nigel,
I use a V700 for medium format.
1) I bought the Better Scanning holder. Much better than the Epson supplied one. More sturdy. Adjustable height. And no, the V700/750 does not have autofocus. Which is why adjustable height is needed.
2) Still had a flatness problem like you. The AN glass idea is OK, but the cost made me pause (four strips of film in holder). So I went downtown to a framing supplies store, and asked for "anti-reflection" glass cut to size. Actually, it's lightly frosted on one or two sides. Just make sure the glass sits above the film, with a frosted face pressing against the film's curvature. Generally this means that the emulsion will be facing down, and you have to tick the "mirror" box in the scanning software.
This takes care of most of the film's surface. The short sides at the two ends are still free to curl away from the glass. I take care of that by taping these ends to the glass before inserting into the trenches of the holder. Works for me. Possibly impractical for 35mm film.